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Dr. Juan Gnecco

Dr. Juan Gnecco is a Colombian-American scientist and an Assistant Professor in the Dept. of Biomedical Engineering at Tufts University. He is the principal investigator of the Laboratory of Reproductive Engineering and an associate principal investigator in the Mother Infant Research Institute (MIRI) at Tufts Medical Center. His overarching research vision lies at the interface of women’s health and engineering to understand the immune-endocrine mechanisms driving both reproductive physiology and disease pathogenesis. As a trained reproductive biologist with extensive experience in bioengineering, he merges interdisciplinary approaches to dissect the complex and dynamic nature of the female reproductive tract. Dr. Gnecco first obtained a B.S. in Biotechnology from Rutgers University followed by a Ph.D in Cellular and Molecular Pathology from Vanderbilt University Medical Center (VUMC). He then conducted his post-doctoral training at Massachusetts Institute of Technology (MIT) where he led efforts to transform the human clinical relevance of 3-dimensional (3D) reproductive tract models. He has been awarded three rounds of funding from Gates Foundation (2018-present) for his work building phenotypic screening models of the female reproductive tract. He is the consortium lead for the World Endometriosis Research Foundation (WERF) consortium to unify experimental organoid models for endometriosis, a member of the Gates Foundation Global Health Integrative Organoid Consortium (2021) and was selected as a Rising Star in Engineering and Health by Columbia University (2020)​

Juan S. Gnecco PhD

Assistant Professor

Biomedical Engineering

Juan.Gnecco@tufts.edu

Lab Members and Alumni

Meet the team!

Dedication. Expertise. Passion.

Get to know the dedicated minds driving our scientific endeavors! Each member brings a unique set of skills, experiences, and perspectives to the table. Together, we're a powerhouse of innovation and knowledge, working tirelessly to unravel the mysteries of female reproductive health.

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PhD Candidate

Lizzie Marr (she/they)

Lizzie received their B.S. in Biomedical Engineering at the Georgia Institute of Technology. Shortly thereafter, Lizzie moved to Boston, MA to work in the biotech industry in research and development, working on numerous organ-on-chip systems utilizing primary human tissues and microfluidics. While working in industry, Lizzie also pursued an M.S. in Materials Science and Engineering at Boston University, co-advised by Drs Joyce Wong and Brett Isenberg. Their Master's thesis was focused on understanding how uterine myocytes respond to mechanical strain as an in vitro model to explore mechanisms related to preterm birth. Now, Lizzie is a PhD student at Tufts, pursuing a project focused on how endometrial dysfunction impacts fertility in the Gnecco Lab. Outside of lab, Lizzie loves to spend time outdoors, rock climbing, hiking, and backpacking in the White Mountains!

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PhD Student

Gianna Scibilio (she/her)

Gianna is a 3rd year Ph.D. student, studying the endometrial microenvironment and the role that nerve fibers play in endometrial disease progression. She graduated Magna Cum Laude from the University of Florida, with her bachelors degree in Biomedical Engineering. During undergrad, she worked on research in biomaterial-cell interactions and the early developmental pathways of embryonic stem cells.

Favorite Hobby: Going to concerts of all kinds (she’s been to 30+ so far!)

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Research Technician

Mar Alonso Riquelme (she/her)

Mariana, also known as Mar, holds a Bachelor's degree in Biotechnology Engineering from Tecnológico de Monterrey in Mexico City. With four years of research experience spanning biomaterials, drug delivery, tissue engineering, and therapeutics, she has contributed to groundbreaking work in different labs. At the Harvard-MIT Artzi Lab, she focused on biomaterial-based immunotherapy for melanoma and glioblastoma. At UNAM's Hernández-Muñoz Lab, she explored the pharmacological repurposing of an HIV drug. Currently, Mar is the Research Tech in the Gnecco Lab, where she leads a project investigating specialized pro-resolving lipid mediators (SPMs) using the lab's endometrial organoid models to understand their role in resolving chronic inflammation in endometriosis.

Outside the lab, Mar enjoys rock climbing, spending time with her dog Lola, painting, and exploring museums.

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PhD student

Reagan Bushok (she/her)

Reagan is a second‑year Ph.D. student in Biomedical Engineering in the Gnecco Lab and an NSF Graduate Research Fellowship recipient. She earned her B.S. in Biological Engineering from Purdue University, where she conducted research on vaginal metabolites and their role in hormone signaling, immune response, and host–microbiome interactions, co‑advised by Prof. Douglas Brubaker and Prof. Leopold Green. She also gained industry experience by completing two internships at Regeneron Pharmaceuticals, focusing on optimizing therapeutic antibody production and silencing target genes in hematological disease. In the Gnecco Lab, Reagan studies how endometrial‑like tissue invades the peritoneum in superficial peritoneal endometriosis, exploring whether this process is driven by pre‑programmed endometrial cells or a receptive, altered mesothelium (the “seed or soil” theory). She also serves as the lab’s Social Chair. Outside the lab, Reagan enjoys traveling, exploring Boston, trying new coffee shops, and visiting cool museums!

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Undergraduate Student

Manavi Vajhallya (she/her)

Manavi is an undergraduate student at Tufts University pursuing her B.S. in Biomedical Engineering. As a pre-med student, she loves learning more about the human body, and is currently enjoying learning about endometriosis in the Gnecco Lab. Outside of the lab, Manavi loves to dance, read, and crochet!

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Master's Student

Brianna Starling (she/her)

Brianna has a Bachelor's degree in Biomedical Engineering from Tufts University. During her senior year, she joined the Gnecco Lab, focusing on histology to help analyze samples, as well as studying endometrial lesions. She also worked with the lab as part of her capstone project, where she helped to develop a novel device for reproductive care. Now, Brianna is pursuing her Master's at Tufts again, as a double Jumbo, researching vasculature in the placenta. In her free time, she enjoys reading, watching anime, and music.

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Undergraduate Student

Manek Khedia (she/her)

Manek is currently a junior from Claremont, CA studying Biochemistry. Outside of research, Manek is a part of Tufts Sex Health Representatives and Tufts JumboRaas. In her free time, Manek enjoys spending time with her loved ones, trying new food, crocheting, and watching movies.

 

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Master's Student

Siqi/Krystal Zhang (she/her)

Krystal received her Bachelor’s degree in Biological Science from Zhejiang University in China. With a strong interest in understanding women’s health issues, she had two years of experience in researching the correlation between ferroptosis and ovarian insufficiency. Currently, Krystal is a master’s student in the Bioengineering program at Tufts University. Her research focuses on establishing a CRISPR system for genetically engineering endometrial epithelial organoids. In her free time, Krystal loves movies, music, singing, reading, cooking, and hanging out with friends.

Alumni

Jazmine Richardson - Undergraduate (she/her) 2023

Sofia Del Castillo - Undergraduate (she/her) 2023

Manek Khedia - Undergraduate (she/her) 2025

Siqi/Krystal Zhang - Master's (she/her) 2025

Grace Hamilton - Master's (she/her) 2025

Brianna Starling - Master's (she/her) 2025

Lab Pets

Introducing our "Lab Pets" - the fluffy, four-legged scientists who bring a touch of pawsitive energy and a dose of tail-wagging enthusiasm to our otherwise buttoned-up lab coats. Meet the adorable sidekicks and get ready to be charmed by their antics and infectious smiles as they paws for a moment in the spotlight! 🐾

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Luna

Chief Purrformance Evaluator

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Ricky Bobby

Specialist in Retrieving Data (and Balls)

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Lola

Head of Naptime Research

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Micron

Meow-ssistant Manager

Laboratory of Reproductive Health

©2024 by THE GNECCO LAB OF REPRODUCTIVE ENGINEERING.

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